A Broadway lead from 1900 who, while her brothers John and Lionel were becoming film stars, established herself as "the first lady of the American stage." Barrymore's screen performances were sporadic, but included an outstanding role in "Rasputin and the Empress" (1932), which co-starred both her brothers. She began making more film appearances as wry, crusty but usually good-hearted matriarchs in the 1940s, winning a best supporting actress Oscar for her performance as Cary Grant's mother in "None But the Lonely Heart" (1944). Other especially notable performances were in "The Spiral Staircase" (1946), "The Farmer's Daughter" (1947), "Pinky" (1949), "Kind Lady" (1951), and "Deadline U.S.A." (1952).